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July07-offprint-Chakraborty.pdf

A lot of issues in modern science are interdisciplinary in nature and require coordinated efforts from physics, chemistry, biology and many other disciplines. The phenomena of mutation of the DNA code is one of those problems. The oxidative damage of DNA is a significant source for mutations in living cells that results in aging, carcinogenesis and many types of human cancers, plus it is linked to diseases such as AIDS, Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. Originally, mutation of the hereditary code was considered to be primarily a biological problem, but later investigations have clearly revealed that it requires contributions from physicists as well.